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Introduction of guanidine hydrochloride(50-01-1)

Guanidine hydrochloride(50-01-1), chemical name is aminomethyl formamidine hydrochloride, its structural formula: NH = C (NH2) 2 · HCl, the formula: CH6ClN3. It is a white or yellowish lump having a melting point of 181 to 183 °C and a relative density of 1.354 at 25 ° C. The pH of the 4% aqueous solution is 6.4 and the solubility in 100 g of the following solution at 20 ° C: 200 g / 100 g of water, 76g / 100g methanol, 24g / 100g ethanol, almost insoluble in acetone, benzene and ether. It can be used as medicine, pesticide, dye and other organic synthesis intermediates, is the manufacture of sulfadiazine, sulfamethine pyrimidine, sulfamethazine pyrimidine and other drugs and folic acid an important raw material, can also be used as synthetic fiber antistatic agent.

Guanidine acetic acid is mainly used in pharmaceutical organic synthesis intermediates, but also as food or feed additives, there are many other beneficial effects: guanidine acetic acid and its salt in acid solution has a good stability, in the absorption and utilization will not be converted to creatinine; with antibacterial activity, animal experiments also show that it can effectively prevent bacterial infections, such as staphylococcal infection (Stanley Drug Products Inc., USA); enhance animal immune function, Animal reproductive performance; can reduce the impact of heat stress on animals, thereby reducing the animal mortality in high temperature environment, it may be because guanidine acetic acid in vivo conversion to creatine, creatine has a strong water system, It helps to maintain the secretion of insulin in the pancreas. In this respect, the effect of guanidine acetic acid is stronger than that of creatine, and insulin can promote the absorption of glucose and amino acid in muscle cells, so as to promote the absorption of glucose and amino acids in muscle cells. Promote protein synthesis, and other insulin can also promote muscle absorption of creatine, reduce muscle tissue degradation rate.



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