About Us  
     View  
     History  
     Honors  
     Culture  
   
  News Center

 

Determination of Sodium Dodecyl Sulfate(cas 151-21-3) in Non - Ducar Tablets by High Performance Liquid Chromatography - Mass Spectrometry

A method for the determination of sodium dodecyl sulfate(cas 151-21-3) in nonbreaks tablets by high performance liquid chromatography - mass spectrometry was established. 

Methods: The mobile phase was prepared by using Eclipse plus C18 (100 mm × 4.6 mm, 3.5 μm) column with acetonitrile-0.1 mol.L-1 acetamide (50:50), electrospray ionization (ESI-), single ion (SIM) detection mode. 

Results: Under the optimized conditions, the retention time of sodium dodecyl sulfate(cas 151-21-3) was 8.5 min and the concentration was in the range of 0.1007 ~ 1.007μg.mL-1 (r = 0.9999), the recovery was between 98% and 102%(RSD = 1.1%). 

Conclusion: The method is simple, rapid, accurate and reproducible. It is suitable for the determination of sodium dodecyl sulfate(cas 151-21-3) in tablets.

 

 

Copyright(C)2016 , XZL Bio-Technology Co., Ltd. All Rights Reserved.  Supported by  LookChem Site Administration Enterprise E-mail 50-01-1