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Sodium p-styrenesulfonate(2695-37-6) act as comonomer

Polyethylene glycol methyl ether methacrylate as macromonomer, hexafluorobutyl methacrylate, sodium p-styrenesulfonate(2695-37-6) as comonomer, using macromonomer graft copolymerization method, prepared a Anionic Fluoride Amphiphilic Graft Copolymer P (HFMA-co-SSS) -g-PEG.

The molecular structure of the copolymer was characterized by FTIR, 1H-NMR and 19F-NMR. The critical micelle concentration (CMC) of P (HFMA-co-SSS) -g-PEG was determined by surface tension method. The results of dynamic light scattering (DLS) show that the micelle size increases with the increase of micelle solution concentration and PEG branching. Fluorescence spectroscopy has been studied by fluorescence spectroscopy. (HFMA-co-SSS) -g-PEG self-assembled micelles and bovine serum albumin (BSA). The results showed that the anionic fluorinated amphiphilic graft copolymer could weaken the fluorescence intensity of BSA (HFMA-co-SSS) -g-PEG micelles and P (HFMA-co-SSS) were investigated by transmission electron microscopy (TEM). The fluorescence intensity of P (HFMA-co-SSS) -g-PEG micelles and P (HFMA-co-SSS ) -g-PEG /BSA aggregates.

The results show that P (HFMA-co-SSS) -g-PEG can self-assemble into the micelles with obvious core-shell structure in aqueous solution. With the decrease of fluorine chain, the copolymer micelles are changed from foliage to regular (HFMA-co-SSS) -g-PEG micelles showed significant adsorption to BSA molecules.



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